Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4334391 | Current Opinion in Neurobiology | 2010 | 8 Pages |
Abstract
By forming close contacts with synapses, astrocytes secrete neuroactive substances and remove neurotransmitters, thus influencing the processing of information by the nervous system. Here, we review recent work on astrocytes and their roles in regulating neuronal function and synaptic plasticity. Astrocytes are organized as networks and communicate with each other, thereby affecting larger neural circuits. They also provide a link between neurons and the vasculature, potentially changing the cerebral microcirculation. Recent work has provided insights into the relative contributions of specific astrocytic cues and transporters to synaptic transmission, plasticity, and animal behavior.
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Sónia Paixão, Rüdiger Klein,