Article ID Journal Published Year Pages File Type
4336249 Journal of Neuroscience Methods 2009 7 Pages PDF
Abstract
The ESD algorithm is based on the high light absorbance of the iris and pupil relative to the eyelid and takes advantage of the unique conditions found in primate physiological recordings (minimal area of sclera and head fixation). The ESD algorithm is as accurate as a human observer, and is not vulnerable to variance inherent to human decisions that it requires (i.e., eye location setting, training set classification and threshold setting). The temporal resolution with standard interlaced digital cameras is 17-20 ms. This is sufficient for the detection of eye state changes during electrophysiological recordings including spontaneous blinking and eye blink conditioning, as demonstrated here. Furthermore, the ESD tool can be applied to other physiological areas of research in which changes in eye state are critical to analyzing neuronal activity.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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