Article ID Journal Published Year Pages File Type
4336265 Journal of Neuroscience Methods 2008 7 Pages PDF
Abstract
To observe neural activity in animals engaged in natural behavior, it is often desirable to minimize or eliminate restraint of the animal. We have developed a simple system for recording from single units in unrestrained cats. An implant with multiple guide tubes and a tiny microdrive is placed inside the recording chamber. An indwelling Pt-Ir microelectrode is advanced incrementally during recording sessions that occur over a period of weeks or months. Electrodes can be easily replaced. We obtain excellent recording stability, and also have been able to sample extensively from a region of cortex or brain stem in a single animal. The essential electronics have been miniaturized and sewn into a light-weight walking jacket, so that we can collect data from a cat who is not connected to any fixed equipment.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
, ,