Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4337810 | Neuroscience | 2013 | 11 Pages |
Abstract
- Exercise training has an impact on brain function and increases neurogenesis.
- High-running capacity animals have better spatial memory and express less Ogg1.
- Exercise increased SIRT1 expression and decreased levels of acetylated Ogg1.
- Exercise increased hippocampal function and transiently decreased repair of genomic 8-oxoG.
Keywords
8-oxoguanine DNA glycosylase-1APE1OGG1LCR8-oxoGHCRTBS-TNGFBERGADHDACHRPTBSDNPHTSAERK5-bromo-2′-deoxyuridine8-oxo-7,8-dihydroguanineglutamic acid decarboxylaseSSBsAbasicacetylatedBrdUDNA repairTris-buffered salineTrichostatin Abase excision repairsingle-strand breaksnerve growth factorNADNAMNAD, nicotinamide adenine dinucleotideNicotinamidehistone deacetylaseHippocampusexerciseHorseradish peroxidaseextracellular signal-regulated kinase
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Neuroscience (General)
Authors
L. Sarga, N. Hart, L.G. Koch, S.L. Britton, G. Hajas, I. Boldogh, X. Ba, Z. Radak,