| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4338071 | Neuroscience | 2013 | 8 Pages |
Abstract
⺠Ammonia inhibits LTP, a cellular model of memory, via neurosteroid production. ⺠Ammonia enhances neurosteroid immunostaining in pyramidal neurons. ⺠Finasteride is used to antagonize 5α-reductase, an enzyme for neurosteroidgenesis. ⺠Finasteride overcomes ammonia-mediated LTP inhibition. ⺠Enhanced neurosteroid immunostaining by ammonia is blocked by finasteride.
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Authors
Y. Izumi, N. Svrakic, K. O'Dell, C.F. Zorumski,