Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4338180 | Neuroscience | 2012 | 8 Pages |
Abstract
⺠MrgprC11 agonist BAM8-22 cross-sensitized scratching evoked by PAR-2 agonist. ⺠MrgprA3 agonist chloroquine cross-sensitized BAM8-22-evoked scratching. ⺠Histamine cross-sensitized chloroquine- and BAM8-22-evoked scratching. ⺠PAR-2 agonist cross-sensitized chloroquine-evoked scratching and DRG cell responses. ⺠PAR-2 is a peripheral target to reduce sensitization associated with chronic itch.
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Authors
T. Akiyama, M. Tominaga, A. Davoodi, M. Nagamine, K. Blansit, A. Horwitz, M.I. Carstens, E. Carstens,