Yohimbine anxiogenesis in the elevated plus maze is disrupted by bilaterally disconnecting the bed nucleus of the stria terminalis from the central nucleus of the amygdala

► The central amygdala and lateral bed nucleus are directly connected. ► Disconnecting lesions did not alter baseline behavior in the elevated plus maze (EPMZ). ► Bilateral disconnecting lesions blocked yohimbine anxiogenesis in the EPMZ. ► EPMZ responses to increased noradrenergic signaling require intra-limbic connections.