| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4338220 | Neuroscience | 2012 | 10 Pages |
Abstract
⺠Deletion of profilin1 in the brain leads to Purkinje cell loss. ⺠Purkinje cell loss begins around P15 and progresses into adulthood. ⺠PC-specific inactivation of profilin1 does not affect Purkinje cell survival. ⺠Purkinje cells complexity is largely preserved in Nes-Cre:Pfn1flx/flx mice. ⺠Profilin1 is not critical for parallel fiber-Purkinje cell synapse function.
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Neuroscience
Neuroscience (General)
Authors
J.A. Kullmann, A. Neumeyer, I. Wickertsheim, R.T. Böttcher, M. Costell, J.W. Deitmer, W. Witke, E. Friauf, M.B. Rust,