| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4338282 | Neuroscience | 2012 | 10 Pages |
Abstract
⺠Effects of nicotinic receptor agonists on hemorrhagic injury were examined. ⺠α7 nicotinic receptor agonist PNU-282987 protected striatal neurons. ⺠PNU-282987 inhibited activation of microglia/macrophages in the perihematoma region. ⺠PNU-282987 had no effect on hematoma expansion and edema formation.
Keywords
SDSiNOSnAChRNeuroinflammationMRIinducible isoform of nitric oxide synthaseMagnetic resonance imagingTUNELintracerebral hemorrhagesodium dodecyl sulfateHemorrhagic strokebasal gangliaterminal deoxynucleotidyl transferase-mediated dUTP nick-end labelingNeuroprotectionICHnicotinic acetylcholine receptorNicotinic receptor
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Authors
M. Hijioka, H. Matsushita, H. Ishibashi, A. Hisatsune, Y. Isohama, H. Katsuki,