Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4338286 | Neuroscience | 2012 | 7 Pages |
Abstract
⺠tPA treatment of stroke increases brain hemorrhage, BBB leakage in T1DM rats. ⺠tPA treatment of stroke fails to improve functional outcome in T1DM rats. ⺠tPA treatment of stroke increases RAGE, MMP-9 and TLR4 expression in T1DM rats. ⺠Increased inflammatory response may contribute to the failed tPA effect on T1DM rats.
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Neuroscience
Neuroscience (General)
Authors
R. Ning, M. Chopp, T. Yan, A. Zacharek, C. Zhang, C. Roberts, X. Cui, M. Lu, J. Chen,