Article ID Journal Published Year Pages File Type
4338286 Neuroscience 2012 7 Pages PDF
Abstract
► tPA treatment of stroke increases brain hemorrhage, BBB leakage in T1DM rats. ► tPA treatment of stroke fails to improve functional outcome in T1DM rats. ► tPA treatment of stroke increases RAGE, MMP-9 and TLR4 expression in T1DM rats. ► Increased inflammatory response may contribute to the failed tPA effect on T1DM rats.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
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