| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4338329 | Neuroscience | 2012 | 13 Pages |
Abstract
⺠First in vivo study of AMPAR density at thalamic neuron synapses in stargazer mice. ⺠Selective loss of AMPARs in inhibitory reticular thalamic neuron synapses in stargazer mutants. ⺠Number of AMPARs is unchanged at corticothalamic synapses of ventral posterior thalamus. ⺠The loss of excitation on inhibitory neurons may underlie the epilepsy in these mice.
Keywords
PSDtransmembrane AMPA receptor regulatory proteinVDCCGluARTNGAERSTARPAMPAREPSCα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptorEDTAEthylenediaminetetraacetic acidPost-synaptic densityexcitatory postsynaptic currentgranule cellGenetic Absence Epilepsy Rats from Strasbourgreticular thalamic nucleusVoltage-dependent calcium channelGlutamate receptor
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Authors
Z. Barad, O. Shevtsova, G.W. Arbuthnott, B. Leitch,