Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4338374 | Neuroscience | 2012 | 12 Pages |
Abstract
â¶Acetyl-l-carnitine maintained mitochondrial function in spinal cord-injured rats. â¶Daily ALC treatment increased tissue sparing and hind limb locomotion after SCI. â¶ALC fostered specific neuroprotection of cholinergic neurons in spinal cord lamina X. â¶Sparing of “CPG” propriospinal neurons was associated with behavioral recovery. â¶Targeting mitochondrial dysfunction with ALC after SCI renders neuroprotection.
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
S.P. Patel, P.G. Sullivan, T.S. Lyttle, D.S.K. Magnuson, A.G. Rabchevsky,