Article ID Journal Published Year Pages File Type
4338374 Neuroscience 2012 12 Pages PDF
Abstract
▶Acetyl-l-carnitine maintained mitochondrial function in spinal cord-injured rats. ▶Daily ALC treatment increased tissue sparing and hind limb locomotion after SCI. ▶ALC fostered specific neuroprotection of cholinergic neurons in spinal cord lamina X. ▶Sparing of “CPG” propriospinal neurons was associated with behavioral recovery. ▶Targeting mitochondrial dysfunction with ALC after SCI renders neuroprotection.
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Life Sciences Neuroscience Neuroscience (General)
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