| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4338531 | Neuroscience | 2012 | 16 Pages |
Abstract
â¶We examined the effect of SDF1 gene delivered at different phases of stroke. â¶Pre-stroke delivery of SDF1 gene elicits immediate effects through neuroprotection. â¶Pre-stroke delivery of SDF1 gene also confers delayed effects because of neurogenesis. â¶SDF1 delivery in the subacute stage generates only delayed beneficial effects. â¶SDF1 might have a wide therapeutic time window in the treatment of stroke.
Keywords
polysialic acid neural cell adhesion moleculehpfHRPDcxNeuNPSA-NCAMGFPMCAOGFAPNSC5-bromo-2-deoxyuridinePDMSPBSmNSSCXCL12MOImiddle cerebral artery occlusionBrdUELISAEnzyme-linked immunosorbent assaydoublecortinNeural stem cellIschemic strokeCMVcytomegalovirusstromal cell-derived factor 1NeuroprotectionPhosphate-buffered salinehigh-power fieldmodified neurological severity scoreNeurogenesisneuronal nucleiHorseradish peroxidaseglial fibrillary acid proteingreen fluorescent proteinmultiplicity of infection
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Authors
J. Yoo, J.-J. Seo, J.-H. Eom, D.-Y. Hwang,