| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4339029 | Neuroscience | 2011 | 10 Pages |
Abstract
â¶Acute ethanol (75 mM) transiently enhanced firing rate of VTA-DA neurons. ⶠAcute ethanol (75 mM) increased frequency of GABAergic-mIPSCs. â¶Mu-opioid receptor activation altered GABA release but not VTA-DA firing rate. â¶GABAA receptor blockade enhanced ethanol stimulation of VTA-DA firing. â¶GABAA receptor agonist uncovers inhibitory effect of ethanol on firing rate.
Keywords
MORNACMesolimbicaCSFTTXsIPSCsmIPSCsVTACeAElectrophysiologyinhibitory synaptic transmissiontetrodotoxinanalysis of varianceANOVAminiature inhibitory postsynaptic currentsSpontaneous inhibitory postsynaptic currentsDORDopaminergicartificial cerebral spinal fluidventral tegmental areaNucleus accumbensAlcohol dependenceKORRewarddelta-opioid receptorkappa-opioid receptormu-opioid receptor
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Authors
J.W. Theile, H. Morikawa, R.A. Gonzales, R.A. Morrisett,