| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4339117 | Neuroscience | 2011 | 16 Pages |
Abstract
â¶Fear conditioning induces widespread activation of midbrain serotonergic neurons. â¶Fear-potentiated startle activates specific subsets of midbrain serotonergic neurons. â¶Activation of midbrain serotonergic neurons correlates with amygdala activation. â¶These results suggest a role of an amygdala-raphe circuit in fear responses.57
Keywords
MPFCdorsal raphe nucleus, caudal partdorsal raphe nucleus, ventral partDRVdorsal raphe nucleus, interfascicular partTphDABDRDCRFCECPBSTCEMPBSCelDRCFpsLSDBLADRI3,3′-diaminobenzidine tetrahydrochlorideAnxietyUrocortin 2immunoreactivesodium phosphate bufferFearleast significant differencerapheserotonergicSerotonincorticotropin-releasing factormedial prefrontal cortexconditioned stimulusPhosphate-buffered salinebasolateral amygdaloid nucleusdorsal raphe nucleusdorsal raphe nucleus, dorsal partcentral amygdaloid nucleusFear-potentiated startleacoustic startletryptophan hydroxylase
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Authors
B.M. Spannuth, M.W. Hale, A.K. Evans, J.L. Lukkes, S. Campeau, C.A. Lowry,