| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4339175 | Neuroscience | 2010 | 8 Pages |
Abstract
â¶S1P increased the rate of AMPA-mEPSCs in CA3 but not other regions of hippocampus. â¶SphK-catalyzed S1P formation is a prerequisite for mossy fiber-CA3 LTP. â¶S1P plays a significant role in the hippocampal function such as spatial learning.
Keywords
PSSSphKevoked excitatory postsynaptic currentaCSFeEPSCmEPSCS1PNMDARfEPSPHFSSmall interfering RNAsiRNASphingosine kinasesphingosine 1-phosphatehigh frequency stimulationlong-term potentiationLTPminiature excitatory postsynaptic currentMemoryPopulation spikesartificial cerebrospinal fluidKnockout miceHippocampusfield excitatory postsynaptic potentialsN-methyl-d-aspartate receptorS1P receptor
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Authors
T. Kanno, T. Nishizaki, R.L. Proia, T. Kajimoto, S. Jahangeer, T. Okada, S. Nakamura,