| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4339267 | Neuroscience | 2011 | 20 Pages |
Abstract
â¶Generation and validation of Kiss1-Cre mouse lines. â¶Kiss1 neurons in the arcuate nucleus (only) are direct target of leptin. â¶Kiss1 neurons coexpress melanocortin 4 receptor (MC4R). â¶Most of Kiss1 neurons in the AVPV/PeN (75%) are GABAergic. â¶Kiss1 neurons in the arcuate nucleus (95%) are glutamatergic.
Keywords
ERαGnRHCre-recombinaseBACSLEPRMC4RβgalGAD-67FACSVGLUT2qPCRGFPAVPVHBSSquantitative RT-PCRβ-galactosidasePENfluorescence activated cell sortingArcLeptinHank's balanced salt solutionmelanocortinarcuate nucleusperiventricular nucleusanteroventral periventricular nucleusgonadotropin releasing hormonegreen fluorescent proteinbacterial artificial chromosomesEstrogen receptor αLeptin receptor
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Authors
R.M. Cravo, L.O. Margatho, S. Osborne-Lawrence, J. Jr, S. Atkin, A.L. Bookout, S. Rovinsky, R. Frazão, C.E. Lee, L. Gautron, J.M. Zigman, C.F. Elias,