| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4342139 | Neuroscience | 2007 | 9 Pages |
Abstract
We conclude that behavioral and electrophysiological differences detected in vivo in rats exposed to an auditory EE are accompanied and possibly caused by selective changes in cortical excitatory transmission. Our data suggest that auditory EE selectively enhances excitatory glutamatergic synaptic transmission in layer II/III without greatly altering inhibitory GABAergic transmission.
Keywords
IPSCQX314interpulse intervalmEPSCPPRDNQXIPID-2-amino-5-phosphonopentanoic acidNMDARAPVNMDAAEPHEPESAMPARaCSFN-methyl-d-aspartate6,7-dinitroquinoxaline-2,3-dioneEPSCN-(2-hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)Excitation/inhibition balanceinhibitory postsynaptic currentexcitatory postsynaptic currentminiature excitatory postsynaptic currentBehaviorauditory evoked potentialHigh-frequencyLow-frequencyartificial cerebrospinal fluidEnriched environmentNeuronal modelingpaired pulse ratioPerforated patchPatch-clampAMPA receptorN-methyl-d-aspartate receptor
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Authors
J.A. Nichols, V.P. Jakkamsetti, H. Salgado, L. Dinh, M.P. Kilgard, M. Atzori,