Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4342738 | Neuroscience | 2007 | 12 Pages |
Abstract
These results indicated that BK caused a [Ca2+]i increase and depolarization in rat myenteric neurons through the activation of B2 receptors, which was partly associated with PGE2 released from glial cells in response to BK. It is suggested that a neuron-glial interaction plays an important role in the effect of BK in the rat myenteric plexus.
Keywords
VDCCCOXHEPESD-MEMEGTAFura-2cDNAComplementary DNA[Ca2+]icyclooxygenaseFura-2 acetoxymethyl esterImmunoreactivitybradykininELISAEnzyme-linked immunosorbent assayGastrointestinalintracellular Ca2+ concentrationFura-2 AMDulbecco’s modified eagle’s mediumEnteric Neuronprostaglandinafter-hyperpolarizationPatch-clampVoltage-dependent Ca2+ channel
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Authors
M. Murakami, T. Ohta, K.-I. Otsuguro, S. Ito,