Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4344071 | Neuroscience Letters | 2013 | 5 Pages |
Abstract
⺠Chronic LY341495 down-regulates 5-HT2A binding in mouse somatosensory cortex. ⺠This effect does not occur in mGlu2-KO mice. ⺠Chronic LY341495 decreases head-twitch behavior and cellular responses induced by LSD. ⺠These findings suggest that repeated blockade of mGlu2 reduces 5-HT2A-dependent effects of LSD.
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Authors
José L. Moreno, Terrell Holloway, Vinayak Rayannavar, Stuart C. Sealfon, Javier González-Maeso,