Article ID Journal Published Year Pages File Type
4344071 Neuroscience Letters 2013 5 Pages PDF
Abstract
► Chronic LY341495 down-regulates 5-HT2A binding in mouse somatosensory cortex. ► This effect does not occur in mGlu2-KO mice. ► Chronic LY341495 decreases head-twitch behavior and cellular responses induced by LSD. ► These findings suggest that repeated blockade of mGlu2 reduces 5-HT2A-dependent effects of LSD.
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Life Sciences Neuroscience Neuroscience (General)
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