| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4344090 | Neuroscience Letters | 2013 | 5 Pages |
Abstract
⺠The ATG5 gene promoter was analyzed in sporadic PD patients and healthy controls. ⺠One novel heterozygous variant, 106774459T>A, was identified in one PD patient. ⺠This variant significantly enhanced transcriptional activity of the ATG5 gene promoter. ⺠ATG5 transcript level in the same PD patient was significantly elevated. ⺠The variant identified in PD may contribute to the PD onset as a risk factor.
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Authors
Dongfeng Chen, Cuiping Zhu, Xuenan Wang, Xungang Feng, Shuchao Pang, Wenhui Huang, Robert G. Hawley, Bo Yan,