| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4344312 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠The PC12 cells apoptosis was increased under hypoxia condition mimicked by CoCl2. ⺠Coculture of BM-MSCs with PC12 cells significantly decreased cell apoptosis. ⺠CoCl2 induced upregulation of EPO expression in BM-MSCs. ⺠EPOsiRNA inhibited the expression of EPO and cytoprotective effect of BM-MSCs. ⺠The expression of EPO is required for BM-MSCs-mediated cytoprotective effect.
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Authors
Shi-Jing Mo, Qian Zhong, Yan-Fang Zhou, David B. Deng, Xiu-Quan Zhang,