Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4344337 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠Threshold tracking can non-invasively provide data on axonal membrane properties. ⺠Increased persistent Na+ current (Nap) is related to neurodegeneration. ⺠Threshold tracking monitored the excitability changes by ranolazine, a selective Nap blocker. ⺠Ranolazine treatment demonstrated a long-term effect on suppression of Nap.
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Authors
Hiroyuki Nodera, Seward B. Rutkove,