| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4344368 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠We investigated the neuroprotective effect of 20(R)-Rg3 against transient focal cerebral ischemia in rats. ⺠20(R)-Rg3 alleviated neurological deficit and decreased the volume of infarction. ⺠20(R)-Rg3 significantly decreased the number of TUNEL-positive cells. ⺠20(R)-Rg3 reduced the expressions of calpain I and caspase-3 mRNA. ⺠20(R)-Rg3 could protect brain against injury induced by cerebral ischemia in rats.
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Authors
Bo He, Peng Chen, Jianyu Yang, Yu Yun, Xiaochao Zhang, Renhua Yang, Zhiqiang Shen,