| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4344378 | Neuroscience Letters | 2012 | 4 Pages |
Abstract
⺠ATP contributes to the development of central sensitization (CS) in medullary nociceptive neurons. ⺠Application of purinergic agonist to the rat tooth pulp induces CS in medullary nociceptive neurons. ⺠Central sensitization can be blocked by pulp application of the purinergic antagonist TNP-ATP. ⺠Central sensitization can be attenuated by medullary application of TNP-ATP.
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Authors
Pavel S. Cherkas, Jonathan O. Dostrovsky, Barry J. Sessle,