Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4344435 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠ERK-mediated signaling activity in RPE cells is elevated quickly (in 30 min) upon retinectomy. ⺠MEK-ERK signaling is intensified by itself through up-regulation of the expression of constituent molecules in the pathway. ⺠Blockade of initial MEK-ERK signaling inhibits cell-cycle re-entry of RPE cells.
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Authors
Aki Mizuno, Hirofumi Yasumuro, Taro Yoshikawa, Wataru Inami, Chikafumi Chiba,