Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury

Article ID	Journal	Published Year	Pages	File Type
4344600	Neuroscience Letters	2012	6 Pages	PDF

Abstract

âº Repetitive closed-skull TBI results in reduced axial and mean diffusivity. âº DTI alterations in white matter were detectable at 7 days but not 24Â h post-injury. âº Amyloid precursor protein accumulation is absent despite diffusion tensor alterations.

Keywords

APP DTI TBI axial diffusivity TAI Traumatic axonal injury Traumatic brain injury Axonal injury radial diffusivity diffusion tensor imaging mean diffusivity amyloid precursor protein