| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4344833 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠We examine the neuroprotective effect of SMTP-7 on transient focal cerebral ischemia. ⺠SMTP-7 significantly reduced infarction volume 24 h after reperfusion. ⺠SMTP-7 reduced reactive oxygen species production and MMP-9 expression. ⺠SMTP-7 has the intrinsic neuroprotective effect on transient focal cerebral ischemia.
Keywords
MCASMTPDAPITTCCCAMMP-9tPAECAICAHETROSEmissionTransient focal cerebral ischemiaTriphenyltetrazolium chlorideBBBmiddle cerebral arteryexternal carotid arteryinternal carotid arterycommon carotid arteryTissue-type plasminogen activatorMatrix metalloproteinase-9Brain–blood barrierExcitationHydroethidineReactive oxygen species
Related Topics
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Neuroscience
Neuroscience (General)
Authors
Yosuke Akamatsu, Atsushi Saito, Miki Fujimura, Hiroaki Shimizu, Moataz Mekawy, Keiji Hasumi, Teiji Tominaga,