Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4344864 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠MPTP produced decreases in striatal DA which partially recovered 18 months later. ⺠By contrast, striatal 5-HT was increased 18 months after MPTP treatment. ⺠In the cortex, decreases in NE were transient but those in 5-HT were long-lasting. ⺠Only striatal DA and NE exhibited age-related vulnerability to MPTP. ⺠5-HT neurons lack the plasticity exhibited by DA neurons to MPTP toxicity.
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Authors
Twum A. Ansah, Marcus C. Ferguson, Tultul Nayyar, Ariel Y. Deutch,