Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4344901 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠There is a developmental switch from NR2B to NR2A expression in synaptic membranes. ⺠NR1/NR2B is the main NMDA receptors (NMDAR) in extrasynaptic membranes at P7. ⺠NR2B phosphorylation at Y1472 and Y1252 is higher in adult synaptic membranes. ⺠At P7, phosphorylation of NR2B at Y1336 is associated with extrasynaptic NMDAR. ⺠STEP expression increases, while p38 decreases with development extrasynaptically.
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Authors
Xiangning Jiang, Renatta Knox, Praneeti Pathipati, Donna Ferriero,