| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4344924 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠AMPK activator, AICAR, activates NPY but not POMC neurons in the hypothalamic arcuate nucleus by promoting extracellular Ca2+ influx. ⺠ICV AICAR-induced food intake is blocked by NPY Y1 receptor antagonist. ⺠Activation of AMPK stimulates ARC NPY neurons through Ca2+ influx, thereby causing NPY-dependent food intake.
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Authors
Daisuke Kohno, Hideyuki Sone, Shigeyasu Tanaka, Hideharu Kurita, Darambazar Gantulga, Toshihiko Yada,