Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4344973 | Neuroscience Letters | 2011 | 6 Pages |
Abstract
⺠Gene expression profiles were compared in RHA-I vs. RLA-I rats (microarray). ⺠14 genes were up-regulated and 24 were down-regulated in RLA-I vs. RHA-I rats. ⺠Based on their brain functions, seven genes were selected for RT-PCR validation. ⺠Differential expression of CAMKK2, CRHBP, EPHX2, HOMER3 and PRL was validated. ⺠These genes are linked to behavioral traits differentially expressed in Roman rats.
Keywords
FDRMMLVRT-PCRQTLCaMKsDEPCcDNAw/vcomplementary deoxyribonucleic acidribonucleic acidRNAAnxietyGene expressionQuantitative trait lociVersusdiethylpyrocarbonateHypothalamic-pituitary-adrenal axisRoman ratsHPAmillilitersmmolmillimolecDNA microarraynanogramreal-time reverse transcription-polymerase chain reactionweight/volumehigh responderslow responders
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Authors
Marta Sabariego, M. José Gómez, Ignacio Morón, Carmen Torres, Alberto Fernández-Teruel, Adolfo Tobeña, Toni Cañete, José A. MartÃnez-Conejero, José A. Horcajadas, Francisco J. Esteban,