| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4345378 | Neuroscience Letters | 2011 | 4 Pages |
Abstract
ⶠThe present study evaluates by means of immunohistochemistry of tyrosine hydroxylase, the effects of chronic Al exposure in adulthood or since intra-uterine age on the dopaminergic neurons. ⶠOur results show that chronic exposure to Al-contaminated water significantly reduced TH-immunoreactive neurons in the substantia nigra. ⶠThe effect of Al is more severe in addicted since the intra-uterine age. ⶠThese changes may affect brain levels of DA with consequence on locomotor activity.
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Authors
Hasna Erazi, Samir Ahboucha, Halima Gamrani,