Article ID Journal Published Year Pages File Type
4345394 Neuroscience Letters 2011 5 Pages PDF
Abstract
▶ Domoic acid is an excitotoxin that induces COX2 expression in the brain. ▶ Properly dosed COX2 inhibitors protect sensitive CA1 and CA3 neurons from excitotoxicity. ▶ Properly dosed COX2 inhibitors provide protection against lethality of excitotoxicity. ▶ Improper dosing of COX2 inhibitors can aggravate domoic acid excitotoxicity.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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