Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4345412 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠Successful prophylaxis will require a focus on more than one pathophysiological process. ⺠Choice of experimental model depends on the specific experimental issue to be addressed. ⺠Disinhibition and new excitatory synapse formation are key prophylactic targets. ⺠Enhancing trophic support by BDNF may “rescue” malfunctioning injured interneurons. ⺠Blockade of thrombospondin actions at a 2δ-1 receptors after injury is antiepileptogenic.
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Authors
Huifang Li, Whitney McDonald, Isabel Parada, Leonardo Faria, Kevin Graber, D. Koji Takahashi, Yunyong Ma, David Prince,