Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4345541 | Neuroscience Letters | 2011 | 4 Pages |
Abstract
⺠Transmeningeal acetylcholine (Ach) induces seizures in the rat neocortex. ⺠Transmeningeal muscimol can prevent Ach-induced neocortical seizures in rats. ⺠Daily transmeningeal muscimol maintains its antiepileptic efficacy for 3 weeks. ⺠Periodic transmeningeal muscimol does not induce tolerance for 3 weeks.
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Neuroscience (General)
Authors
Hai M. Tang, Jacqueline A. French, Ruben I. Kuzniecky, Orrin Devinsky, Nandor Ludvig,