Article ID Journal Published Year Pages File Type
4345567 Neuroscience Letters 2011 5 Pages PDF
Abstract
▶ Adenosine reduced IPSC frequency of presynaptic PVN cells projecting to medulla. ▶ Adenosine effect was blocked by antagonist, and mimicked by agonist of A1 receptor. ▶ Adenosine increased paired-pulse ratio of evoked IPSCs. ▶ In conclusion, adenosine inhibits GABA release via presynaptic A1 receptors. ▶ Results indicate potential roles of adenosine in regulation of sympathetic outflow.
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