Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4347111 | Neuroscience Letters | 2009 | 4 Pages |
Abstract
The current study aimed to determine genes that changed continuously throughout the postnatal developmental process of the rat visual cortex. Tissue samples were taken at postnatal day 0, day 10 (before eye opening), day 20 (before the critical period) and day 45 (end of development) and subjected to microarray and real-time RT-PCR analyses. A temporal pattern of expression was revealed for 24 genes that continuously increased (18 genes) or decreased (6 genes) as visual cortex development progressed and were common among all age groups. Our data provide a relevant set of genes whose expression levels correlate with visual cortex development and represent a novel group that may affect temporal-specific regulation.
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Authors
Liu Yang, Zhujuan Pan, Lihua Zhou, Shaochun Lin, Kaili Wu,