Article ID Journal Published Year Pages File Type
4349477 Neuroscience Letters 2007 5 Pages PDF
Abstract

Major depression is one of the most disabling disorders. Yet, the pathogenesis of this mental disorder is poorly understood. Hippocampus is generally believed to be associated with pathogenesis of depression. In this study, we adopted a proteomic approach to examine possible alterations of protein expression in the hippocampus of a rat depression model. Our results suggest that neurogenesis in hippocampus may play an important role in the pathogenesis of major depression.

Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
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