Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4349477 | Neuroscience Letters | 2007 | 5 Pages |
Abstract
Major depression is one of the most disabling disorders. Yet, the pathogenesis of this mental disorder is poorly understood. Hippocampus is generally believed to be associated with pathogenesis of depression. In this study, we adopted a proteomic approach to examine possible alterations of protein expression in the hippocampus of a rat depression model. Our results suggest that neurogenesis in hippocampus may play an important role in the pathogenesis of major depression.
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Neuroscience
Neuroscience (General)
Authors
Jun Mu, Peng Xie, Ze-Song Yang, De-Lan Yang, Fa-Jin Lv, Tian-You Luo, Yong Li,