Article ID Journal Published Year Pages File Type
4351431 Neuroscience Research 2013 10 Pages PDF
Abstract
► Study of neuroinflammation and its role in a hamster model of Parkinson's disease. ► Combination of 6-OHDA with prednisolone, minocycline or minocycline + prednisolone. ► The three treatments attenuated microglia activation after a single 6-OHDA injection. ► Only in prednisolone group dopamine fibers in the ipsilateral striatum statistically recovered. ► The recovery correlated with lower mRNA levels of TNF-α and iNOS.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
, , ,