Remodeling of hippocampal network in pilocarpine-treated mice expressing synaptopHluorin in the mossy fiber terminals

Article ID	Journal	Published Year	Pages	File Type
4351469	Neuroscience Research	2012	7 Pages	PDF

Abstract

âº SynaptopHluorin was used for direct investigation of mossy fiber sprouting. âº Its ectopic expression was evidenced after pilocarpine-induced seizures. âº Its abnormal expression was also enhanced in some layers of CA3a region. âº More widespread reorganization of network is suggested than previously expected.

Keywords

SPH TSQ ZnT3 Stratum lucidum SLM stratum oriens TLE IML Synaptogenesis stratum radiatum stratum pyramidale Epilepsy Transgenic seizure Zinc transporter 3 temporal lobe epilepsy Zinc mossy fiber inner molecular layer Hippocampus Pilocarpine