| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4351498 | Neuroscience Research | 2012 | 6 Pages |
Abstract
⺠Social isolation (SI) of mice has been studied as an animal model of neuropsychiatric disorders. ⺠The effects of SI on the expression levels of Egr were examined in the frontal cortex. ⺠SI suppressed the expression of Egr-1 protein and Egr-1 mRNA in cortical neurons. ⺠It had no effect on the expression levels of other Egr family members. ⺠The decrease in Egr-1 in the frontal cortex may be involved in SI-induced behavioral abnormalities.
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Authors
Kinzo Matsumoto, Kazuya Ono, Hirofumi Ouchi, Ryohei Tsushima, Yukihisa Murakami,