Article ID Journal Published Year Pages File Type
4351521 Neuroscience Research 2013 10 Pages PDF
Abstract
► The possibility that the residue E97 of ChR2 is involved in ion flux is tested. ► The charge at this position strongly influenced the ion permeation. ► The charge replacement retarded the Gd3+-dependent channel block. ► The E97 would interact with a permeating cation to facilitate the dehydration. ► It is also a primary binding site of Gd3+ in the outer pore region of the channel.
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Life Sciences Neuroscience Neuroscience (General)
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