Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4351521 | Neuroscience Research | 2013 | 10 Pages |
Abstract
⺠The possibility that the residue E97 of ChR2 is involved in ion flux is tested. ⺠The charge at this position strongly influenced the ion permeation. ⺠The charge replacement retarded the Gd3+-dependent channel block. ⺠The E97 would interact with a permeating cation to facilitate the dehydration. ⺠It is also a primary binding site of Gd3+ in the outer pore region of the channel.
Keywords
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Saki Tanimoto, Yuka Sugiyama, Tetsuo Takahashi, Toru Ishizuka, Hiromu Yawo,