Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4351649 | Neuroscience Research | 2011 | 4 Pages |
Abstract
Recent technical advances in electrophysiological recording and functional imaging from the brain of living animals have promoted our understandings of the brain function, but these in vivo experiments are still technically demanding and often suffer from spontaneous pulsation, i.e., brain movements caused by respiration and heartbeat. Here we report that thoracotomy suppresses the motion artifact to a practically negligible level. This simple method will be useful in a wide variety of in vivo experiments, such as patch-clamp physiology, and optical imaging of neurons, glial cell, and blood vessels.
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Authors
Nobuyoshi Matsumoto, Yuji Takahara, Norio Matsuki, Yuji Ikegaya,