Article ID Journal Published Year Pages File Type
4352125 Neuroscience Research 2011 9 Pages PDF
Abstract
► We stably expressed mutant NMDAR on HEK 293T cell surface. ► Autoantibodies from anti-NMDAR encephalitis patients recognize extracellular epitopes of GluRzeta1 subunit and induce internalization of it. ► The specificity of the on-cell Western was improved at 37 °C. ► Our assays will be valuable for the diagnosis, evaluation of clinical treatments, and follow up of anti-NMDAR encephalitis.
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