| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4353371 | Progress in Neurobiology | 2013 | 12 Pages |
Abstract
⺠Recent findings have linked the NPS system to drug dependence. ⺠NPS activity may contribute to vulnerability to addiction, especially relapse. ⺠Effects of NPS on drugs of abuse are mediated by CRF and Hcrt-1/Ox-A systems. ⺠Interactions between NPS, CRF, and the Hcrt-1/Ox-A systems in addiction are analyzed. ⺠The use of NPS receptor antagonists as a potential treatment for addiction is analyzed.
Keywords
intracerebroventricularACOCRFMSPcyclic adenosine mono phosphatePaVN-methyl-d-aspartic acidCRF1ICVPEFNMDABNSTGPCRAVPVTAVMHNeuropeptide Sneuropeptide S receptorDMHEPNCPPNPSRCRF receptor 1ACTHeGFPBLAEPMmRNAPFCOX1basolateral amygdalacAMPCeAG protein coupled receptorNPsmessenger RNAarginine-vasopressinlateral amygdalaCentral amygdalaGamma aminobutyric acidAddictionAlcoholReinstatementelevated plus mazelateral ventricleconditioned place preferenceself-administrationintraperitonealDopaminecorticotrophin releasing factorHypothalamic pituitary adrenalprefrontal cortexMotor cortexlocus coeruleusHPAventral tegmental areaknock outnoradrenalinewild typeEndopiriform nucleusanterior cortical amygdaloid nucleusbed nucleus of stria terminalisdorsomedial hypothalamic nucleusparaventricular nucleusadrenocorticotropic hormonelateral hypothalamusRewardenhanced green fluorescent proteinCocaineGABAOrexin 1 receptor
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Authors
Nazzareno Cannella, Marsida Kallupi, Barbara Ruggeri, Roberto Ciccocioppo, Massimo Ubaldi,