| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4353381 | Progress in Neurobiology | 2013 | 17 Pages |
Abstract
⺠Interest in blood-borne proteomic biomarkers in neurological research is mounting. ⺠Preanalytical variables are frequently overlooked in blood proteomic analyses. ⺠Preanalytical bias can be due to technical and biological factors. ⺠Another source of variability is proteome perturbation caused by sample processing. ⺠Bioinformatics is invaluable for the storing and processing of proteomics data.
Keywords
IEFR/Tproteomics standards initiativeMIAPEHUPOHAPSSOPs2D-PAGEPTMsNFTsRMSPSIPISAβLAPSMALDI-TOFIgGm/zMS/MSEDTAEthylenediaminetetraacetic acidSDS-PAGEtwo-dimensional polyacrylamide gel electrophoresissodium dodecyl sulphate polyacrylamide gel electrophoresisXMLimmunoglobulin Gamyloid betaAlzheimer's diseaseAnalytical biaspost-translational modificationsisoelectric focusingRoom temperatureStandard operating proceduresextensible markup languageHuman Proteome OrganizationSerumlumbar punctureMass spectrometryTandem mass spectrometrySELDI-TOFCSFCerebrospinal fluidMatrix-Assisted Laser Desorption/Ionization Time-of-FlightReference materialsProtease inhibitorsneurofibrillary tanglesMass-to-charge ratioProteomicsPlasmaliquid chromatographyHPLChigh-performance liquid chromatographyLow-abundance proteins
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Neuroscience (General)
Authors
Simone Lista, Frank Faltraco, Harald Hampel,