| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 4355268 | Hearing Research | 2012 | 9 Pages |
Abstract
⺠Mouse cochlear function was compared between isoflurane and ketamine-based anaesthetics. ⺠Isoflurane increased ABR thresholds over time, input/output slope was unaffected. ⺠ABR thresholds were stable with ketamine-based anaesthetic. ⺠Isoflurane likely inhibits cochlear nerve fibre recruitment. ⺠Ketamine-induced DPOAE changes indicate an outer hair cell site of action.
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Authors
Jennie M.E. Cederholm, Kristina E. Froud, Ann C.Y. Wong, Myungseo Ko, Allen F. Ryan, Gary D. Housley,