Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
4355410 | Hearing Research | 2012 | 9 Pages |
Abstract
⺠The inner-ear immortomouse cell line (HEI-OC1) efficiently takes up gentamicin. ⺠Aminoglycoside antibiotics activate caspase-dependent cell death pathways. ⺠Aminoglycoside antibiotics do not result in HEI-OC1 cell death. ⺠Cisplatin treatment leads to HEI-OC1 cell death. ⺠Cellular senescence is not observed in HEI-OC1 cells after gentamicin treatment.
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Authors
Fu-Quan Chen, Kayla Hill, Ya-Jun Guan, Jochen Schacht, Su-Hua Sha,