Plasma membrane Ca2+-ATPase isoforms in frog crista ampullaris: Identification of PMCA1 and PMCA2 specific splice variants

Frog crista ampullaris hair cells lack a Na/Ca exchanger, therefore PMCAs are the only mechanism of Ca2+ extrusion. The coexpression of specific isozymes in the different cellular compartments responds to the need of a fine regulation of both basal and dynamic Ca2+ levels at the apical and basal pole of the cell.